Tillsonburg is located in Southwestern Ontario, at the southern end of Oxford County, and serves as a regional centre for industry, commerce, health care, and recreation. Tillsonburg enjoys a labour and consumer population in excess of 100,000 people within a 30 minute driving distance and is home to a variety of industries exporting products around the world, making Tillsonburg a profitable centre for business and industry.

Excellent access is provided to the town by road, rail, and air. Conveniently situated on highway #3, Tillsonburg is directly connected to highway 401 and is strategically centered between Detroit and Buffalo and less than a two hour drive from Toronto. A business location in Tillsonburg provides access to the manufacturing heartland of North America, all within one days trucking drive from Tillsonburg.